Trip information

Departure: Harrisburg, PA
Arrival: Des Moines, IA
Fastest route: 28h 55min
Distance: 1622km
Cheapest route: $129
Transfers: 2
Bus companies: Greyhound

Cheap bus schedules leaving on Friday

One Passenger / One Trip

7:55am

Harrisburg, PA

Harrisburg Bieber Greyhound Station

5:55pm

Des Moines, IA

Des Moines Bus Station

35h 0min

++ 2 layovers

$129

7:55am

Harrisburg, PA

Harrisburg Bieber Greyhound Station

11:59am

Pittsburgh, PA

Intermodal Station

4h 4min

Greyhound

$25

7h 46min layover

7:45pm

Pittsburgh, PA

Intermodal Station

5:25am

Chicago, IL

95th & Dan Ryan CTA

10h 40min

Greyhound

$59

4h 40min layover

10:05am

Chicago, IL

95th & Dan Ryan CTA

5:55pm

Des Moines, IA

Des Moines Bus Station

7h 50min

Greyhound

$45

7:55am

Harrisburg, PA

Harrisburg Bieber Greyhound Station

5:55pm

Des Moines, IA

Des Moines Bus Station

35h 0min

++ 2 layovers

$195

7:55am

Harrisburg, PA

Harrisburg Bieber Greyhound Station

4:30pm

Cleveland, OH

Greyhound Station

8h 35min

Greyhound

$105

7h 15min layover

11:45pm

Cleveland, OH

Greyhound Station

5:45am

Chicago, IL

95th & Dan Ryan CTA

7h 0min

Greyhound

$45

4h 20min layover

10:05am

Chicago, IL

95th & Dan Ryan CTA

5:55pm

Des Moines, IA

Des Moines Bus Station

7h 50min

Greyhound

$45

11:15am

Harrisburg, PA

Harrisburg Bieber Greyhound Station

5:55pm

Des Moines, IA

Des Moines Bus Station

31h 40min

++ 2 layovers

$134

11:15am

Harrisburg, PA

Harrisburg Bieber Greyhound Station

6:10pm

Pittsburgh, PA

Intermodal Station

6h 55min

Greyhound

$30

1h 35min layover

7:45pm

Pittsburgh, PA

Intermodal Station

5:25am

Chicago, IL

95th & Dan Ryan CTA

10h 40min

Greyhound

$59

4h 40min layover

10:05am

Chicago, IL

95th & Dan Ryan CTA

5:55pm

Des Moines, IA

Des Moines Bus Station

7h 50min

Greyhound

$45

2:00pm

Harrisburg, PA

Harrisburg Bieber Greyhound Station

5:55pm

Des Moines, IA

Des Moines Bus Station

28h 55min

++ 2 layovers

$134

2:00pm

Harrisburg, PA

Harrisburg Bieber Greyhound Station

6:05pm

Pittsburgh, PA

Intermodal Station

4h 5min

Greyhound

$30

1h 40min layover

7:45pm

Pittsburgh, PA

Intermodal Station

5:25am

Chicago, IL

95th & Dan Ryan CTA

10h 40min

Greyhound

$59

4h 40min layover

10:05am

Chicago, IL

95th & Dan Ryan CTA

5:55pm

Des Moines, IA

Des Moines Bus Station

7h 50min

Greyhound

$45

2:00pm

Harrisburg, PA

Harrisburg Bieber Greyhound Station

5:55pm

Des Moines, IA

Des Moines Bus Station

28h 55min

++ 2 layovers

$195

2:00pm

Harrisburg, PA

Harrisburg Bieber Greyhound Station

10:35pm

Cleveland, OH

Greyhound Station

8h 35min

Greyhound

$105

1h 10min layover

11:45pm

Cleveland, OH

Greyhound Station

5:45am

Chicago, IL

95th & Dan Ryan CTA

7h 0min

Greyhound

$45

4h 20min layover

10:05am

Chicago, IL

95th & Dan Ryan CTA

5:55pm

Des Moines, IA

Des Moines Bus Station

7h 50min

Greyhound

$45

6:10pm

Harrisburg, PA

Harrisburg Bieber Greyhound Station

5:30am

Des Moines, IA

Des Moines Bus Station

36h 20min

++ 2 layovers

$139

6:10pm

Harrisburg, PA

Harrisburg Bieber Greyhound Station

12:55am

Pittsburgh, PA

Intermodal Station

6h 45min

Greyhound

$35

2h 35min layover

3:30am

Pittsburgh, PA

Intermodal Station

5:00pm

Chicago, IL

95th & Dan Ryan CTA

14h 30min

Greyhound

$59

3h 45min layover

8:45pm

Chicago, IL

95th & Dan Ryan CTA

5:30am

Des Moines, IA

Des Moines Bus Station

8h 45min

Greyhound

$45

9:55pm

Harrisburg, PA

Harrisburg Bieber Greyhound Station

5:30am

Des Moines, IA

Des Moines Bus Station

32h 35min

++ 2 layovers

$195.5

9:55pm

Harrisburg, PA

Harrisburg Bieber Greyhound Station

6:45am

Cleveland, OH

Greyhound Station

8h 50min

Greyhound

$109.5

1h 30min layover

8:15am

Cleveland, OH

Greyhound Station

5:00pm

Chicago, IL

95th & Dan Ryan CTA

9h 45min

Greyhound

$41

3h 45min layover

8:45pm

Chicago, IL

95th & Dan Ryan CTA

5:30am

Des Moines, IA

Des Moines Bus Station

8h 45min

Greyhound

$45

Overview

Traveling from Harrisburg to Des Moines by bus

First departure
7:55am
Avg price
$160.21
Carriers
1
Last arrival
5:30am

Bus information Harrisburg - Des Moines

The Harrisburg - Des Moines route has approximately 7 frequencies and its minimum duration is around 28h 55min. It is important you book your ticket in advance to avoid running out, since $129 tickets tend to run out quickly.
The distance between Harrisburg and Des Moines is around 1622 kilometers and the bus companies that can help you in your journey are: Greyhound.
Remember that the number of transfers to be made will be at least 2 so in some cases you should book the tickets separately.

  • Trips per day 7
  • Direct trips 0

How long does it take to get from Harrisburg to Des Moines by bus?

Bus journey may vary depending on the state of the roads. The minimum duration is usually around 28h 55min to cover 1622 kilometers.

I'm looking for cheap tickets for this route ...

According to our data, the cheapest ticket costs $129 and leaves Harrisburg Bieber Greyhound Station. If you decide to make this journey you will have to do 2 stops before reaching Des Moines Bus Station.

  • Avg duration 32h 37min
  • Cheapest price $129

What time does the last bus leave?

Last bus leaves at 9:55pm from Harrisburg Bieber Greyhound Station and arrives at 5:30am at Des Moines Bus Station. It will take 32h 35min, its price is $195.5 and the number of changes will be 2.

Are there any direct routes between Harrisburg and Des Moines?

We do not have direct routes in our database. The minimum number of transfers will be 2 and the total duration of the trip will be approximately 35h 0min.

  • Last bus 9:55pm
  • Transfers 2

What are the bus stations in Harrisburg?

  • Harrisburg Bieber Greyhound Station
    411 Market St
    Harrisburg, PA 17101

What are the bus stations in Des Moines?

  • Des Moines Bus Station
    1501 2nd Ave North
    Des Moines, IA 50314
We use cookies to enhance your browsing experience. By using this site, you agree to our use of cookies. More information: Cookies Policy