Trip information

Departure: Hyannis, MA
Arrival: Des Moines, IA
Fastest route: 34h 40min
Distance: 2221km
Cheapest route: $161
Transfers: 2
Bus companies: Greyhound, Bonanza / Peter Pan

Cheap bus schedules leaving on Friday

One Passenger / One Trip

5:00am

Hyannis, MA

Plymouth & Brockton Terminal

5:55pm

Des Moines, IA

Des Moines Bus Station

37h 55min

++ 2 layovers

$162

Multiple companies

5:00am

Hyannis, MA

Plymouth & Brockton Terminal

6:35am

Boston, MA

South Station Bus Terminal

1h 35min

Bonanza / Peter Pan

$22

0h 25min layover

7:00am

Boston, MA

South Station Bus Terminal

11:20am

New York, NY

Port Authority Bus Terminal

4h 20min

Greyhound

$21

5h 55min layover

5:15pm

New York, NY

Port Authority Bus Terminal

5:55pm

Des Moines, IA

Des Moines Bus Station

25h 40min

Greyhound

$119

6:15am

Hyannis, MA

Plymouth & Brockton Terminal

5:55pm

Des Moines, IA

Des Moines Bus Station

36h 40min

++ 2 layovers

$161

Multiple companies

6:15am

Hyannis, MA

Plymouth & Brockton Terminal

7:50am

Boston, MA

South Station Bus Terminal

1h 35min

Bonanza / Peter Pan

$22

0h 10min layover

8:00am

Boston, MA

South Station Bus Terminal

12:40pm

New York, NY

Port Authority Bus Terminal

4h 40min

Greyhound

$20

4h 35min layover

5:15pm

New York, NY

Port Authority Bus Terminal

5:55pm

Des Moines, IA

Des Moines Bus Station

25h 40min

Greyhound

$119

6:15am

Hyannis, MA

Plymouth & Brockton Terminal

5:55pm

Des Moines, IA

Des Moines Bus Station

36h 40min

++ 2 layovers

$171.5

Multiple companies

6:15am

Hyannis, MA

Plymouth & Brockton Terminal

8:05am

Providence, RI

1 Sabin St

1h 50min

Bonanza / Peter Pan

$30.5

0h 30min layover

8:35am

Providence, RI

1 Sabin St

2:25pm

New York, NY

Port Authority Bus Terminal

5h 50min

Greyhound

$22

2h 50min layover

5:15pm

New York, NY

Port Authority Bus Terminal

5:55pm

Des Moines, IA

Des Moines Bus Station

25h 40min

Greyhound

$119

7:30am

Hyannis, MA

Plymouth & Brockton Terminal

5:55pm

Des Moines, IA

Des Moines Bus Station

35h 25min

++ 2 layovers

$161

Multiple companies

7:30am

Hyannis, MA

Plymouth & Brockton Terminal

9:05am

Boston, MA

South Station Bus Terminal

1h 35min

Bonanza / Peter Pan

$22

0h 25min layover

9:30am

Boston, MA

South Station Bus Terminal

2:45pm

New York, NY

Port Authority Bus Terminal

5h 15min

Bonanza / Peter Pan

$20

2h 30min layover

5:15pm

New York, NY

Port Authority Bus Terminal

5:55pm

Des Moines, IA

Des Moines Bus Station

25h 40min

Greyhound

$119

8:15am

Hyannis, MA

Plymouth & Brockton Terminal

5:55pm

Des Moines, IA

Des Moines Bus Station

34h 40min

++ 2 layovers

$179.5

Multiple companies

8:15am

Hyannis, MA

Plymouth & Brockton Terminal

10:35am

Providence, RI

1 Sabin St

2h 20min

Bonanza / Peter Pan

$30.5

0h 35min layover

11:10am

Providence, RI

1 Sabin St

2:45pm

New York, NY

Port Authority Bus Terminal

3h 35min

Bonanza / Peter Pan

$30

2h 30min layover

5:15pm

New York, NY

Port Authority Bus Terminal

5:55pm

Des Moines, IA

Des Moines Bus Station

25h 40min

Greyhound

$119

10:30am

Hyannis, MA

Plymouth & Brockton Terminal

5:30am

Des Moines, IA

Des Moines Bus Station

44h 0min

++ 2 layovers

$173

Multiple companies

10:30am

Hyannis, MA

Plymouth & Brockton Terminal

12:20pm

Providence, RI

1 Sabin St

1h 50min

Bonanza / Peter Pan

$32

0h 15min layover

12:35pm

Providence, RI

1 Sabin St

6:55pm

New York, NY

Port Authority Bus Terminal

6h 20min

Greyhound

$22

4h 5min layover

11:00pm

New York, NY

Port Authority Bus Terminal

5:30am

Des Moines, IA

Des Moines Bus Station

31h 30min

Greyhound

$119

12:15pm

Hyannis, MA

Plymouth & Brockton Terminal

5:30am

Des Moines, IA

Des Moines Bus Station

42h 15min

++ 2 layovers

$182

Multiple companies

12:15pm

Hyannis, MA

Plymouth & Brockton Terminal

1:50pm

Boston, MA

South Station Bus Terminal

1h 35min

Bonanza / Peter Pan

$22

0h 10min layover

2:00pm

Boston, MA

South Station Bus Terminal

8:00pm

New York, NY

Port Authority Bus Terminal

6h 0min

Greyhound

$41

3h 0min layover

11:00pm

New York, NY

Port Authority Bus Terminal

5:30am

Des Moines, IA

Des Moines Bus Station

31h 30min

Greyhound

$119

12:30pm

Hyannis, MA

Plymouth & Brockton Terminal

5:30am

Des Moines, IA

Des Moines Bus Station

42h 0min

++ 2 layovers

$177

Multiple companies

12:30pm

Hyannis, MA

Plymouth & Brockton Terminal

3:10pm

Providence, RI

1 Sabin St

2h 40min

Bonanza / Peter Pan

$32

1h 20min layover

4:30pm

Providence, RI

1 Sabin St

8:35pm

New York, NY

Port Authority Bus Terminal

4h 5min

Greyhound

$26

2h 25min layover

11:00pm

New York, NY

Port Authority Bus Terminal

5:30am

Des Moines, IA

Des Moines Bus Station

31h 30min

Greyhound

$119

1:45pm

Hyannis, MA

Plymouth & Brockton Terminal

5:30am

Des Moines, IA

Des Moines Bus Station

40h 45min

++ 2 layovers

$171

Multiple companies

1:45pm

Hyannis, MA

Plymouth & Brockton Terminal

3:20pm

Boston, MA

South Station Bus Terminal

1h 35min

Bonanza / Peter Pan

$22

0h 10min layover

3:30pm

Boston, MA

South Station Bus Terminal

7:50pm

New York, NY

Port Authority Bus Terminal

4h 20min

Greyhound

$30

3h 10min layover

11:00pm

New York, NY

Port Authority Bus Terminal

5:30am

Des Moines, IA

Des Moines Bus Station

31h 30min

Greyhound

$119

Overview

Traveling from Hyannis to Des Moines by bus

First departure
5:00am
Avg price
$170.89
Carriers
2
Last arrival
5:30am

Bus information Hyannis - Des Moines

The Hyannis - Des Moines route has approximately 9 frequencies and its minimum duration is around 34h 40min. It is important you book your ticket in advance to avoid running out, since $161 tickets tend to run out quickly.
The distance between Hyannis and Des Moines is around 2221 kilometers and the bus companies that can help you in your journey are: Greyhound, Bonanza / Peter Pan.
Remember that the number of transfers to be made will be at least 2 so in some cases you should book the tickets separately.

  • Trips per day 9
  • Direct trips 0

How long does it take to get from Hyannis to Des Moines by bus?

Bus journey may vary depending on the state of the roads. The minimum duration is usually around 34h 40min to cover 2221 kilometers.

I'm looking for cheap tickets for this route ...

According to our data, the cheapest ticket costs $161 and leaves Plymouth & Brockton Terminal. If you decide to make this journey you will have to do 2 stops before reaching Des Moines Bus Station.

  • Avg duration 38h 55min
  • Cheapest price $161

What time does the last bus leave?

Last bus leaves at 1:45pm from Plymouth & Brockton Terminal and arrives at 5:30am at Des Moines Bus Station. It will take 40h 45min, its price is $171 and the number of changes will be 2.

Are there any direct routes between Hyannis and Des Moines?

We do not have direct routes in our database. The minimum number of transfers will be 2 and the total duration of the trip will be approximately 37h 55min.

  • Last bus 1:45pm
  • Transfers 2

What are the bus stations in Hyannis?

  • Plymouth & Brockton Terminal
    215 Iyannough Rd
    Hyannis, MA 02601

What are the bus stations in Des Moines?

  • Des Moines Bus Station
    1501 2nd Ave North
    Des Moines, IA 50314
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