Trip information

Departure: Orlando, FL
Arrival: Des Moines, IA
Fastest route: 37h 25min
Distance: 2100km
Cheapest route: $169
Transfers: 2
Bus companies: Greyhound

Cheap bus schedules leaving on Thursday

One Passenger / One Trip

5:30am

Orlando, FL

Greyhound Station

5:55pm

Des Moines, IA

Des Moines Bus Station

37h 25min

++ 2 layovers

$172

5:30am

Orlando, FL

Greyhound Station

5:15am

Indianapolis, IN

Bus Station

23h 45min

Greyhound

$95

0h 45min layover

6:00am

Indianapolis, IN

Bus Station

10:00am

Chicago, IL

95th & Dan Ryan CTA

5h 0min

Greyhound

$32

0h 5min layover

10:05am

Chicago, IL

95th & Dan Ryan CTA

5:55pm

Des Moines, IA

Des Moines Bus Station

7h 50min

Greyhound

$45

5:30am

Orlando, FL

Greyhound Station

5:30am

Des Moines, IA

Des Moines Bus Station

49h 0min

++ 2 layovers

$170.5

5:30am

Orlando, FL

Greyhound Station

9:05pm

Nashville, TN

Nashville Greyhound Bus Station

16h 35min

Greyhound

$74

2h 40min layover

11:45pm

Nashville, TN

Nashville Greyhound Bus Station

3:00pm

Chicago, IL

95th & Dan Ryan CTA

15h 15min

Greyhound

$44

5h 45min layover

8:45pm

Chicago, IL

95th & Dan Ryan CTA

5:30am

Des Moines, IA

Des Moines Bus Station

8h 45min

Greyhound

$52.5

6:30am

Orlando, FL

Greyhound Station

5:30am

Des Moines, IA

Des Moines Bus Station

48h 0min

++ 2 layovers

$170.5

6:30am

Orlando, FL

Greyhound Station

10:50pm

Nashville, TN

Nashville Greyhound Bus Station

17h 20min

Greyhound

$74

0h 55min layover

11:45pm

Nashville, TN

Nashville Greyhound Bus Station

3:00pm

Chicago, IL

95th & Dan Ryan CTA

15h 15min

Greyhound

$44

5h 45min layover

8:45pm

Chicago, IL

95th & Dan Ryan CTA

5:30am

Des Moines, IA

Des Moines Bus Station

8h 45min

Greyhound

$52.5

1:00pm

Orlando, FL

Greyhound Station

5:30am

Des Moines, IA

Des Moines Bus Station

41h 30min

++ 2 layovers

$187.5

1:00pm

Orlando, FL

Greyhound Station

9:45am

Indianapolis, IN

Bus Station

20h 45min

Greyhound

$104

1h 15min layover

11:00am

Indianapolis, IN

Bus Station

5:00pm

Chicago, IL

95th & Dan Ryan CTA

7h 0min

Greyhound

$31

3h 45min layover

8:45pm

Chicago, IL

95th & Dan Ryan CTA

5:30am

Des Moines, IA

Des Moines Bus Station

8h 45min

Greyhound

$52.5

1:00pm

Orlando, FL

Greyhound Station

5:30am

Des Moines, IA

Des Moines Bus Station

41h 30min

++ 2 layovers

$169

1:00pm

Orlando, FL

Greyhound Station

1:45am

Nashville, TN

Nashville Greyhound Bus Station

13h 45min

Greyhound

$79.5

1h 15min layover

3:00am

Nashville, TN

Nashville Greyhound Bus Station

5:00pm

Chicago, IL

95th & Dan Ryan CTA

14h 0min

Greyhound

$37

3h 45min layover

8:45pm

Chicago, IL

95th & Dan Ryan CTA

5:30am

Des Moines, IA

Des Moines Bus Station

8h 45min

Greyhound

$52.5

7:50pm

Orlando, FL

Greyhound Station

5:55pm

Des Moines, IA

Des Moines Bus Station

47h 5min

++ 2 layovers

$183

7:50pm

Orlando, FL

Greyhound Station

6:40pm

Indianapolis, IN

Bus Station

22h 50min

Greyhound

$107

3h 50min layover

10:30pm

Indianapolis, IN

Bus Station

5:45am

Chicago, IL

95th & Dan Ryan CTA

8h 15min

Greyhound

$31

4h 20min layover

10:05am

Chicago, IL

95th & Dan Ryan CTA

5:55pm

Des Moines, IA

Des Moines Bus Station

7h 50min

Greyhound

$45

11:35pm

Orlando, FL

Greyhound Station

5:55pm

Des Moines, IA

Des Moines Bus Station

43h 20min

++ 2 layovers

$183

11:35pm

Orlando, FL

Greyhound Station

9:20pm

Indianapolis, IN

Bus Station

21h 45min

Greyhound

$107

1h 10min layover

10:30pm

Indianapolis, IN

Bus Station

5:45am

Chicago, IL

95th & Dan Ryan CTA

8h 15min

Greyhound

$31

4h 20min layover

10:05am

Chicago, IL

95th & Dan Ryan CTA

5:55pm

Des Moines, IA

Des Moines Bus Station

7h 50min

Greyhound

$45

11:35pm

Orlando, FL

Greyhound Station

5:55pm

Des Moines, IA

Des Moines Bus Station

43h 20min

++ 2 layovers

$185

11:35pm

Orlando, FL

Greyhound Station

1:45pm

Nashville, TN

Nashville Greyhound Bus Station

15h 10min

Greyhound

$85

5h 30min layover

7:15pm

Nashville, TN

Nashville Greyhound Bus Station

5:45am

Chicago, IL

95th & Dan Ryan CTA

10h 30min

Greyhound

$55

4h 20min layover

10:05am

Chicago, IL

95th & Dan Ryan CTA

5:55pm

Des Moines, IA

Des Moines Bus Station

7h 50min

Greyhound

$45

Overview

Traveling from Orlando to Des Moines by bus

First departure
5:30am
Avg price
$177.56
Carriers
1
Last arrival
5:55pm

Bus information Orlando - Des Moines

The Orlando - Des Moines route has approximately 8 frequencies and its minimum duration is around 37h 25min. It is important you book your ticket in advance to avoid running out, since $169 tickets tend to run out quickly.
The distance between Orlando and Des Moines is around 2100 kilometers and the bus companies that can help you in your journey are: Greyhound.
Remember that the number of transfers to be made will be at least 2 so in some cases you should book the tickets separately.

  • Trips per day 8
  • Direct trips 0

How long does it take to get from Orlando to Des Moines by bus?

Bus journey may vary depending on the state of the roads. The minimum duration is usually around 37h 25min to cover 2100 kilometers.

I'm looking for cheap tickets for this route ...

According to our data, the cheapest ticket costs $169 and leaves Greyhound Station. If you decide to make this journey you will have to do 2 stops before reaching Des Moines Bus Station.

  • Avg duration 43h 53min
  • Cheapest price $169

What time does the last bus leave?

Last bus leaves at 11:35pm from Greyhound Station and arrives at 5:55pm at Des Moines Bus Station. It will take 43h 20min, its price is $185 and the number of changes will be 2.

Are there any direct routes between Orlando and Des Moines?

We do not have direct routes in our database. The minimum number of transfers will be 2 and the total duration of the trip will be approximately 37h 25min.

  • Last bus 11:35pm
  • Transfers 2

What are the bus stations in Orlando?

  • Greyhound Station
    555 N John Young Pkwy
    Orlando, FL 32805

What are the bus stations in Des Moines?

  • Des Moines Bus Station
    1501 2nd Ave North
    Des Moines, IA 50314
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