Trip information

Departure: Santa Cruz, CA
Arrival: Key West, FL
Fastest route: 78h 15min
Distance: 4659km
Cheapest route: $183
Transfers: 2
Bus companies: Greyhound

Cheap bus schedules leaving on Thursday

One Passenger / One Trip

7:25am

Santa Cruz, CA

Metro Center Bus Station

10:55pm

Key West, FL

Greyhound Station

84h 30min

++ 2 layovers

$183

7:25am

Santa Cruz, CA

Metro Center Bus Station

4:20pm

Los Angeles, CA

Downtown Greyhound Station

8h 55min

Greyhound

$20

2h 25min layover

6:45pm

Los Angeles, CA

Downtown Greyhound Station

2:20pm

Miami, FL

MIA Airport Central Station

64h 35min

Greyhound

$149

4h 5min layover

6:25pm

Miami, FL

MIA Airport Central Station

10:55pm

Key West, FL

Greyhound Station

4h 30min

Greyhound

$14

7:25am

Santa Cruz, CA

Metro Center Bus Station

10:55pm

Key West, FL

Greyhound Station

84h 30min

++ 2 layovers

$202

7:25am

Santa Cruz, CA

Metro Center Bus Station

4:20pm

Los Angeles, CA

Downtown Greyhound Station

8h 55min

Greyhound

$20

2h 25min layover

6:45pm

Los Angeles, CA

Downtown Greyhound Station

8:25am

Orlando, FL

Greyhound Station

58h 40min

Greyhound

$135

4h 35min layover

1:00pm

Orlando, FL

Greyhound Station

10:55pm

Key West, FL

Greyhound Station

9h 55min

Greyhound

$47

8:05am

Santa Cruz, CA

Metro Center Bus Station

10:55pm

Key West, FL

Greyhound Station

83h 50min

++ 2 layovers

$183

8:05am

Santa Cruz, CA

Metro Center Bus Station

5:40pm

Los Angeles, CA

Downtown Greyhound Station

9h 35min

Greyhound

$20

1h 5min layover

6:45pm

Los Angeles, CA

Downtown Greyhound Station

2:20pm

Miami, FL

MIA Airport Central Station

64h 35min

Greyhound

$149

4h 5min layover

6:25pm

Miami, FL

MIA Airport Central Station

10:55pm

Key West, FL

Greyhound Station

4h 30min

Greyhound

$14

8:05am

Santa Cruz, CA

Metro Center Bus Station

10:55pm

Key West, FL

Greyhound Station

83h 50min

++ 2 layovers

$202

8:05am

Santa Cruz, CA

Metro Center Bus Station

5:40pm

Los Angeles, CA

Downtown Greyhound Station

9h 35min

Greyhound

$20

1h 5min layover

6:45pm

Los Angeles, CA

Downtown Greyhound Station

8:25am

Orlando, FL

Greyhound Station

58h 40min

Greyhound

$135

4h 35min layover

1:00pm

Orlando, FL

Greyhound Station

10:55pm

Key West, FL

Greyhound Station

9h 55min

Greyhound

$47

1:40pm

Santa Cruz, CA

Metro Center Bus Station

10:55pm

Key West, FL

Greyhound Station

78h 15min

++ 2 layovers

$185.5

1:40pm

Santa Cruz, CA

Metro Center Bus Station

10:30pm

Los Angeles, CA

Downtown Greyhound Station

8h 50min

Greyhound

$22.5

1h 20min layover

11:50pm

Los Angeles, CA

Downtown Greyhound Station

5:35pm

Miami, FL

MIA Airport Central Station

62h 45min

Greyhound

$149

0h 50min layover

6:25pm

Miami, FL

MIA Airport Central Station

10:55pm

Key West, FL

Greyhound Station

4h 30min

Greyhound

$14

1:40pm

Santa Cruz, CA

Metro Center Bus Station

10:55pm

Key West, FL

Greyhound Station

78h 15min

++ 2 layovers

$204.5

1:40pm

Santa Cruz, CA

Metro Center Bus Station

10:30pm

Los Angeles, CA

Downtown Greyhound Station

8h 50min

Greyhound

$22.5

1h 20min layover

11:50pm

Los Angeles, CA

Downtown Greyhound Station

12:15pm

Orlando, FL

Greyhound Station

57h 25min

Greyhound

$135

0h 45min layover

1:00pm

Orlando, FL

Greyhound Station

10:55pm

Key West, FL

Greyhound Station

9h 55min

Greyhound

$47

10:50pm

Santa Cruz, CA

Metro Center Bus Station

4:55pm

Key West, FL

Greyhound Station

87h 5min

++ 2 layovers

$194.5

10:50pm

Santa Cruz, CA

Metro Center Bus Station

7:25am

Los Angeles, CA

Downtown Greyhound Station

8h 35min

Greyhound

$27.5

5h 20min layover

12:45pm

Los Angeles, CA

Downtown Greyhound Station

8:15am

Miami, FL

MIA Airport Central Station

64h 30min

Greyhound

$149

4h 10min layover

12:25pm

Miami, FL

MIA Airport Central Station

4:55pm

Key West, FL

Greyhound Station

4h 30min

Greyhound

$18

10:50pm

Santa Cruz, CA

Metro Center Bus Station

4:55pm

Key West, FL

Greyhound Station

87h 5min

++ 2 layovers

$209.5

10:50pm

Santa Cruz, CA

Metro Center Bus Station

7:25am

Los Angeles, CA

Downtown Greyhound Station

8h 35min

Greyhound

$27.5

5h 20min layover

12:45pm

Los Angeles, CA

Downtown Greyhound Station

1:50am

Orlando, FL

Greyhound Station

58h 5min

Greyhound

$135

4h 10min layover

6:00am

Orlando, FL

Greyhound Station

4:55pm

Key West, FL

Greyhound Station

10h 55min

Greyhound

$47

11:50pm

Santa Cruz, CA

Metro Center Bus Station

4:55pm

Key West, FL

Greyhound Station

86h 5min

++ 2 layovers

$194

11:50pm

Santa Cruz, CA

Metro Center Bus Station

9:00am

Los Angeles, CA

Downtown Greyhound Station

9h 10min

Greyhound

$27

3h 45min layover

12:45pm

Los Angeles, CA

Downtown Greyhound Station

8:15am

Miami, FL

MIA Airport Central Station

64h 30min

Greyhound

$149

4h 10min layover

12:25pm

Miami, FL

MIA Airport Central Station

4:55pm

Key West, FL

Greyhound Station

4h 30min

Greyhound

$18

11:50pm

Santa Cruz, CA

Metro Center Bus Station

4:55pm

Key West, FL

Greyhound Station

86h 5min

++ 2 layovers

$209

11:50pm

Santa Cruz, CA

Metro Center Bus Station

9:00am

Los Angeles, CA

Downtown Greyhound Station

9h 10min

Greyhound

$27

3h 45min layover

12:45pm

Los Angeles, CA

Downtown Greyhound Station

1:50am

Orlando, FL

Greyhound Station

58h 5min

Greyhound

$135

4h 10min layover

6:00am

Orlando, FL

Greyhound Station

4:55pm

Key West, FL

Greyhound Station

10h 55min

Greyhound

$47

Overview

Traveling from Santa Cruz to Key West by bus

First departure
7:25am
Avg price
$196.7
Carriers
1
Last arrival
4:55pm

Bus information Santa Cruz - Key West

The Santa Cruz - Key West route has approximately 10 frequencies and its minimum duration is around 78h 15min. It is important you book your ticket in advance to avoid running out, since $183 tickets tend to run out quickly.
The distance between Santa Cruz and Key West is around 4659 kilometers and the bus companies that can help you in your journey are: Greyhound.
Remember that the number of transfers to be made will be at least 2 so in some cases you should book the tickets separately.

  • Trips per day 10
  • Direct trips 0

How long does it take to get from Santa Cruz to Key West by bus?

Bus journey may vary depending on the state of the roads. The minimum duration is usually around 78h 15min to cover 4659 kilometers.

I'm looking for cheap tickets for this route ...

According to our data, the cheapest ticket costs $183 and leaves Metro Center Bus Station. If you decide to make this journey you will have to do 2 stops before reaching Greyhound Station.

  • Avg duration 83h 57min
  • Cheapest price $183

What time does the last bus leave?

Last bus leaves at 11:50pm from Metro Center Bus Station and arrives at 4:55pm at Greyhound Station. It will take 86h 5min, its price is $209 and the number of changes will be 2.

Are there any direct routes between Santa Cruz and Key West?

We do not have direct routes in our database. The minimum number of transfers will be 2 and the total duration of the trip will be approximately 84h 30min.

  • Last bus 11:50pm
  • Transfers 2

What are the bus stations in Santa Cruz?

  • Metro Center Bus Station
    920 Pacific Ave
    Santa Cruz, California, 95062

What are the bus stations in Key West?

  • Greyhound Station
    3535 Florida A1A
    Key West
    FL 33040, USA
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